ahajournals.org

Optimal Randomization Designs for Large Multicenter Clinical Trials: From the National Institutes of Health Stroke Trials Network Funded by National Institutes of Health ...

ARCADIA indicates Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke; ASPIRE, Anticoagulation in ICH Survivors for Stroke Prevention and Recovery; DEFUSE 3, ...
ahajournals.org

Network Mendelian Randomization Study Design to Assess Factors Mediating the Causal Link Between Telomere Length and Heart Disease

Although Mendelian randomization techniques can involve fairly computationally intensive analyses, the fundamental principles that guide these study designs are straightforward and if understood ...
JSTOR Daily

Randomization Tests for Systematic Single-Case Designs Are Not Always Appropriate

The authors used a Monte Carlo simulation to examine how the violation of the exchangeability assumption affects empirical Type I error rates of the LMH randomization ...
ascopubs.org

Comparison of Power Between Randomized Discontinuation Design and Upfront Randomization Design on Progression-Free Survival

Chronic Physical Effects and Health Care Utilization in Long-Term Ovarian Germ Cell Tumor Survivors: A Gynecologic Oncology Group Study Enrichment based on molecular characteristics has emerged as an ...
Frontiers

Analyzing safety data for two-stage randomization designs

1 Department of Biostatistics, University of the Free State, Bloemfontein, South Africa 2 Department of Statistical Sciences, University of Padua, Padua, Italy Ensuring patient safety is paramount in ...
JSTOR Daily

Cox Regression Methods for Two-Stage Randomization Designs

Two-stage randomization designs (TSRD) are becoming increasingly common in oncology and AIDS clinical trials as they make more efficient use of study participants to examine therapeutic regimens. In ...