※ Affiliations and titles are as of the end of the research activity. This research area aims to elucidate basic principles in relation to the structure and function of genomes (the principle of ...

The genome structure — how genes are organized within DNA sequences in an organism — is fundamental to the processes and functions of organisms. A team at the University of Tokyo has developed a ...

University of Wisconsin researchers Sushmita Roy and Erika Da-Inn Lee have developed a new computational tool that maps changes in the genome, ultimately helping researchers see DNA’s 3D organization ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living ...

Every cell in your body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Led by postdoctoral fellow Brian Cosgrove, they made hydrogels that mimic tissues of different stiffness and cultured cells on these gels. The researchers then used sequencing tools to quantify RNA ...