R-loops are three-stranded non-canonical nucleic acid structures composed of nascent RNA hybridized with the template DNA strand, leaving the non-template DNA strand displaced. These structures play ...
Despite a positive correlation between R-loops and tumorigenesis, the presumed causality is not experimentally validated. Using a transgenic mouse model in which accumulated R-loops are removed in ...
Edited by Robert Gallo, Institute of Human Virology and Departments of Medicine and Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, and approved January 7, 2021 ...
R-loops are non-canonical, three-stranded nucleic acid structures composed of a DNA:RNA hybrid, a displaced single-stranded (ss)DNA, and a trailing ssRNA overhang. R-loops perform critical biological ...
Altmetric provides a collated score for online attention across various platforms and media. See more details Although HIV-1 integration sites favor active transcription units in the human genome, ...
Type V CRISPR-Cas interference proteins use a single RuvC active site to make RNA-guided breaks in double-stranded DNA substrates, an activity essential for both bacterial immunity and genome editing.
This study is achieved by Professor Wei Xu’s research team from Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences. The research team established mDRIP-seq, a ...
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