EMBO Press

Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets

A deep spatial proteomic analysis of healthy fallopian tube epithelium, matching high-grade serous ovarian cancer (HGSOC) ...
EMBO Press

circ-EGFR is a predictor of response to Cetuximab and a potential target in colorectal cancer

Circ-EGFR was identified as a novel predictive biomarker for cetuximab efficacy in KRAS wild-type metastatic colorectal ...
EMBO Press

Closing the loop on EGFR therapy: decoding cetuximab response through circ-EGFR

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...
EMBO Press

Annexin A7 enhances TIA1 axonal trafficking to counteract pathological aggregation in neurons

TIA1 is a prominent RNA binding protein (RBP) involved in the formation of pathogenic aggregates in neurons. This manuscript shows that the annexin protein family member ANXA7 links TIA1 granules to ...