EMBO Press

Solid trouble: tau and TDP-43 interaction in aggregation and pathology

Both microtubule-binding protein tau and RNA-binding protein TDP-43 have been associated with neurodegenerative diseases, such as Alzheimer’s disease, including in co-pathological deposition with each ...
EMBO Press

A personal journey through academia as a neurodiverse scientist

I recently participated in a collection of interviews for an excellent piece by Julian Nowogrodzki, who presented scientists with ADHD and how we navigate the challenges of academia (Nowogrodzki, 2025 ...
EMBO Press

BACE1 regulates sleep–wake cycle through both enzymatic and non–enzymatic actions

A proteolytically inactive BACE1 knock-in (BACE1-KI, D289N) is compared with a BACE1 knockout (BACE1-KO) mouse to dissect ...
EMBO Press

From microscopes to maps: enabling a new era of open and reproducible data sharing in intravital imaging

In this issue of The EMBO Journal, Pizzagalli and colleagues present proof-of-principle analyses of immune cell motility ...
EMBO Press

CTRP9 engages AdipoR1 and promotes T cell glycolysis and immunity

AdipoR1 selectively recognizes adipokine ligands, differentially shaping T-cell immune outcomes. CTRP9 engages AdipoR1 to ...