Resequencing of the 5′ region of NTRK2 in a clinically and ethnically diverse sample of 190 unrelated individuals uncovered two novel sequence variants (LNG5 and LNG7; Table 1). The two previously ...

Ternary plots illustrating the relative fit of the NREV12, NREV6, and GTR nucleotide substitution models based on weighted AIC scores for 30 dsDNA, 31 dsRNA, 33 ssDNA, and 47 ssRNA virus nucleotide ...

Nucleotide sequence data are being harnessed to identify species, even in cases in which organisms themselves are neither in hand nor witnessed. But how genome-wide sequence divergence maps to species ...

“In a recent study published in PNAS, Sidi et al. (7) leverage an mBART-based (multilingual Bidirectional and Auto-Regressive Transformer) deep-learning approach (Fig. 1) to decode the evolutionary ...

This valuable study revisits the effects of substitution model selection on phylogenetics by comparing reversible and non-reversible DNA substitution models. The authors provide solid evidence that 1) ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, No. 6 (Mar. 15, 1985), pp. 1673-1677 (5 pages) Ornithine decarboxylase (OrnDCase; L-ornithine carboxy-lyase, ...

Henry M. Kronenberg, Barbara E. McDevitt, Joseph A. Majzoub, Jeremy Nathans, Phillip A. Sharp, John T. Potts and Alexander Rich Proceedings of the National Academy of Sciences of the United States of ...

Today EMBL-Bank, the nucleotide sequence database of the European Molecular Biology Laboratory (EMBL), celebrates its 25th anniversary. It was the world’s earliest public database of DNA and RNA ...

Abstract: In this paper, we have proposed a new method that extracts a set of signatures from different nucleotide groups via measuring the distances between the groups. The proposed method not only ...

Modified nucleotide contains one or more synthetic modifications to its phosphate (P), ribose sugar (R), or base (A, T, C, G, U). User should be able to view modified RNA monomers in sequence ...