Background. This study analyzed the relationship between vancomycin area under the concentration-time curve (AUC) and acute kidney injury (AKI) reported across recent studies. Methods. A systematic ...

Background: Vancomycin dosing in critically ill patients typically requires monitoring the area under the concentration-time curve/minimum inhibitory concentration (AUC/MIC), often using at least two ...

Results from a multi-center study of hospitalized adults with MRSA bloodstream infections suggest that vancomycin dosing should be guided by the area under the curve, or AUC, not the AUC/MIC ratio, ...

This study aimed to evaluate whether trough level-guided monitoring can be replaced by area under the concentration-time curve (AUC) and MIC ratio-guided monitoring (AUC/MIC ratio = 400) in patients ...

Vancomycin is a commonly used antibiotic for the treatment of methicillin-resistant Staphylococcus aureus (MRSA), which requires therapeutic drug monitoring (TDM). Guidelines recommend targeting an ...

Researchers have developed a population-based pharmacokinetic model to identify target levels for vancomycin treatment so that infants infected with Staphylococcus aureus receive effective therapy.

Successful Migration to a Vancomycin AUC-dosing Protocol: Evaluation, Implementation and Outcomes in an Acute Care Hospital Setting Vancomycin, an antibiotic medication used to treat serious bacterial ...

ABSTRACT: Background: The 2020 consensus guidelines recommend AUC guided dosing as the preferred monitoring method for vancomycin. AUC based dosing has shown to reduce incidence of acute kidney injury ...