How to Change Google Chrome File Association. When you double-click a file on your computer, Windows may launch an application to run or display the file.

Changing Windows 10 File Associations You can select "Set Defaults by App," highlight "Google Chrome" on the next screen and click "Manage" to configure which files are opened with Chrome.

If you keep Chrome up-to-date without changing any settings, any PDF you download may open within the web browser by default.